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Io Therapeutics, Inc., presents today at the San Antonio Breast Cancer Symposium preclinical studies demonstrating effectiveness of IRX4204, the company’s clinical stage retinoid X nuclear receptor (RXR) agonist compound, for synerg

SPRING, Texas, Dec. 11, 2025 (Korea Bizwire) – Io Therapeutics, Inc., a privately held pharmaceutical company headquartered in Spring, Texas; announced today presentation at the San Antonio Breast Cancer Symposium, in San Antonio, TX; of data from preclinical studies demonstrating effectiveness of IRX4204, the company’s phase II clinical stage retinoid X nuclear receptor (RXR) agonist [...]

Io Therapeutics presents today at the American Society for Hematology Annual Meeting, preclinical studies demonstrating combination treatment with BCMA CAR-T cells plus the company’s RXR agonist compound IRX4204 has synergistic efficacy against human multiple myeloma

SPRING, Texas, Dec. 06, 2025 (Korea Bizwire) – Io Therapeutics, Inc., a privately held pharmaceutical company headquartered in Spring, Texas; announced today collaborative presentations at the 67th American Society of Hematology Annual Meeting and Exposition, in Orlando, Florida; with scientists from the Duke University School of Medicine in Durham, North Carolina; reporting data from preclinical studies [...]

Scientists report studies showing a novel drug repairs myelin and restores nervous system function in a model of multiple sclerosis

HALIFAX, Nova Scotia and SPRING, Texas, Dec. 23, 2024 (Korea Bizwire) – Scientists at Dalhousie University in Halifax, and Io Therapeutics, Inc. in Spring Texas, announced today collaborative publication of data from studies demonstrating effectiveness of the RXR agonist compound IRX4204 in reversing demyelination, and functionally restoring movement in the paralyzed legs of mice subjected [...]

Io Therapeutics, Inc., Announces Presentation of Data from Studies of Its RAR Gamma Agonist Compound IRX5010 in Treatment of a Mouse Model of Triple Negative Breast Cancer, Demonstrating Combination Treatment Effects with an Anti-PDL-1 Monoclonal Antibody Checkpoint Inhibitor

The combination treatment resulted in increased numbers of anti-cancer tumor-infiltrating T-cells; decreased numbers of anti-cancer response inhibiting tumor-infiltrating myeloid derived suppressor cells; and substantial 84% inhibition of tumor growth SPRING, Texas, Dec. 11 (Korea Bizwire) — Io Therapeutics, Inc., presented results from studies done in a mouse model of triple negative breast cancer with the [...]

Io Therapeutics, Inc., announces presentation of data on its RAR gamma agonist compound IRX5010 demonstrating inhibition of tumor infiltrating myeloid derived suppressor cells, promotion of tumor infiltrating T-cells, and effective tumor growth inhibition in murine models of breast, colorectal, and prostate cancers

SPRING, Texas, Nov. 08, 2024 (Korea Bizwire) – Io Therapeutics, Inc., presented results from studies done in breast, colorectal, and prostate cancer models with the company’s newest anti-cancer compound IRX5010, an agonist of the retinoic acid nuclear receptor gamma, which was discovered in the company’s oncology drug program. The presentation titled “RAR Gamma Agonist Compounds [...]

Io Therapeutics, Inc., Presented Today Results from Studies of IRX4204, the Company’s Phase II Clinical Development Stage, Highly Selective RXR Nuclear Receptor Agonist Compound, Supporting Its Potential Use for Treatment of Amyotrophic Lateral Sclerosis (ALS)

SPRING, Texas, July 16, 2024 (Korea Bizwire) – Io Therapeutics, Inc., presented today results from studies of IRX4204, the company’s phase II clinical development stage, highly selective RXR nuclear receptor agonist compound, supporting its potential use for treatment of amyotrophic lateral sclerosis (ALS). The presentation titled “The RXR Nuclear Receptor Agonist Compound IRX4204 is a [...]

Io Therapeutics, Inc., Presented Data from Studies of IRX4204, the Company’s Phase II Clinical Development Stage, Highly Selective Third Generation RXR Nuclear Receptor Agonist Compound, Supporting Its Potential Use for Prevention and Treatment of Normal Aging-related Neurodegeneration, Parkinson’s Disease, and Alzheimer’s Disease

SPRING, Texas, Jul. 9 (Korea Bizwire) — Io Therapeutics, Inc., presented today results from studies done on the potential for prevention and treatment of normal aging-related neurodegeneration, Parkinson’s disease (PD), and Alzheimer’s disease (AD), with its clinical stage experimental therapeutic RXR nuclear receptor agonist compound IRX4204. IRX4204 is a highly potent and highly selective, orally [...]

Io Therapeutics, Inc., Announces Presentation of Data on Induction of Tumor Growth Inhibiting Anti-cancer Immune Responses in Multiple Types of Cancers by a IRX5010, a Novel Retinoic Acid Nuclear Receptor Agonist Compound

SPRING, Texas, Jul. 8 (Korea Bizwire) — Io Therapeutics, Inc., presented today results from studies done in breast, lung, colorectal, and prostate cancer models with the company’s newest anti-cancer compound IRX5010, an agonist of retinoic acid nuclear receptor gamma which was discovered in the company’s oncology drug program. The presentation titled “RAR Gamma Agonist Compounds [...]

Io Therapeutics, Inc., Announces Publication of Data on a Novel Compound Promoting Anti-Cancer Immune Responses

SPRING, Texas, Sept. 12, 2023 (Korea Bizwire) – Io Therapeutics, Inc., announced today the publication in Scientific Reports – Nature Publishing Group, of results from studies done with the company’s novel anti-cancer compound IRX4647, an agonist of the retinoic acid nuclear receptor gamma, discovered in the company’s oncology drug program. The paper, titled “A novel retinoic acid [...]