Extracts derived from the plant’s distinctive cork-like wings have been found to not only prevent but also treat the condition. (Image courtesy of the National Institute of Biological Resources)
SEOUL, Feb. 1 (Korea Bizwire) – In a significant discovery, a research collaboration between the National Institute of Biological Resources and Professor Byun Sanguine of Yonsei University has unveiled the potential of arrowwood, a plant indigenous to Korea, in combating rheumatoid arthritis.
Extracts derived from the plant’s distinctive cork-like wings have been found to not only prevent but also treat the condition.
The study revealed that when arrowwood wing extract was administered to synovial cells obtained from rheumatoid arthritis patients, it demonstrated an anti-inflammatory efficacy 3.2 times greater than methotrexate, a standard treatment for the disease.
Furthermore, the application of this extract to animals suffering from rheumatoid arthritis resulted in significant improvements: a 40% reduction in joint swelling, a 51% decrease in joint damage, and a reduction of over 75% in the levels of inflammatory indicators IL-6 and IL-8 compared to those in untreated animals.
The research team completed a patent application for their findings in August of last year and is preparing to publish their results in the international journal “Phytomedicine,” which focuses on plant-based medicines, in February.
Arrowwood, a plant belonging to the honeysuckle family and known by various names such as Viburnum, is prevalent throughout Korea, particularly in limestone regions on mountain slopes.
Characterized by its height of 1 to 3 meters and the unique cork-like wings along its stems, the plant is utilized in various ways: its leaves are consumed as a delicacy, its branches are used medicinally, and its fruit serves as an insecticide.
Rheumatoid arthritis, an inflammatory autoimmune disorder with unclear origins, is commonly associated with symptoms in the fingers, toes, and knees but can manifest throughout the body, affecting overall health.
This discovery opens up new avenues for natural and potentially more harmonious treatments for those suffering from rheumatoid arthritis, offering a glimmer of hope to patients seeking alternatives to conventional therapies.
Lina Jang (linajang@koreabizwire.com)
